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        Predictions on the final evaluation set submitted by all challenge participants are available here <a href="final-results/tox21-challenge.zip"><b>tox21-challenge.zip</b></a>
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                    <p>	<img src="img/submission-original.jpg" class="thumbnail img-responsive" alt="" /></p> 
                    <ul>
                        <li><a href="http://www.ncats.nih.gov/research/reengineering/tox21/tox21.html">Tox21 at NCATS</a></li>
                        <li><a href="http://epa.gov/ncct/Tox21/" TARGET="_blank">Tox21 at the Environmental Protection Agency</a></li>
                        <li><a href="http://ntp.niehs.nih.gov/?objectid=05F80E15-F1F6-975E-77DDEDBDF3B941CD" TARGET="_blank">
                        Tox21 at the National Toxicology Program/National Institute of Environmental Health Sciences</a></li>
                        <li><a href="http://www.ncats.nih.gov/research/reengineering/tox21/projects/compound-toxicity.html">Tox21 Robot at NCATS</a></li>
                    </ul>

                    <hr>
                    <h4>Key Dates<img src="img/signal.gif" style="vertical-align:text-bottom;"></h4>
                    <p><strong>August 18, 2014</strong><br>NCATS begins accepting submissions</p>
                    <p><strong>November 14, 2014 (11:59 p.m. ET)</strong><br>Registration and submission deadline</p>
                    <p><strong>January 12, 2015</strong><br>Winners announced</p>
                    <p><a class="btn btn-default" href="registration.jsp" role="button">Register Now &raquo;</a></p><br/><br/><br/>
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                <div class="panel-heading"><h3 class="panel-title">Training Datasets <span class="glyphicon glyphicon-file bs-icon"> </span></h3></div>
                <div class="panel-body">
                     <br/>The complete training dataset is available 
                     <a href="download?id=tox21_10k_data_allsdf&sec=">here</a>. 
                     For individual datasets, please use the links below.
                     In the datasets, "1" means active, "0" means inactive.<br/>
                     <br/><p class="datatitle">Nuclear Receptor Signaling Panel</p>
                    <div class="datapanel">
                        <table  class="datatable">
                            <thead>
                                <tr><th>Assay</th><th> SDF</th><th>SMILES</th></tr>
                            </thead>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743040" target="_blank">AR</a></td>
                                <td><a href="#" class="datalink" id="nr-arsdf"></a></td>
                                <td><a href="#" class="datalink" id="nr-arsmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743122" target="_blank">AhR</a></td>
                                <td><a href="#" class="datalink" id="nr-ahrsdf"></a></td> 
                                <td><a href="#" class="datalink" id="nr-ahrsmiles"></a></td>
                            </tr> 
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743053" target="_blank">AR-LBD</a></td>
                                <td><a href="#" class="datalink" id="nr-ar-lbdsdf"></a></td>
                                <td><a href="#" class="datalink" id="nr-ar-lbdsmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743079" target="_blank">ER</a></td>
                                <td><a href="#" class="datalink" id="nr-ersdf"></a></td>
                                <td><a href="#" class="datalink" id="nr-ersmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743077" target="_blank">ER-LBD</a></td>
                                <td><a href="#" class="datalink" id="nr-er-lbdsdf"></a></td>
                                <td><a href="#" class="datalink" id="nr-er-lbdsmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743139" target="_blank">aromatase</a></td>
                                <td><a href="#" class="datalink" id="nr-aromatasesdf"></a></td>
                                <td><a href="#" class="datalink" id="nr-aromatasesmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743140" target="_blank">PPAR-gamma</a></td>
                                <td><a href="#" class="datalink" id="nr-ppar-gammasdf"></a></td>
                                <td><a href="#" class="datalink" id="nr-ppar-gammasmiles"></a></td>
                            </tr>
                        </table>
                    </div> 
						 
                    <br/>
                    <p class="datatitle">Stress Response Panel</p>
                    <div  class="datapanel">
                        <table class="datatable">  
                            <thead>
                                <tr><th>Assay</th><th> SDF</th><th>SMILES</th></tr>
                            </thead>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743219" target="_blank">ARE</a></td> 
                                <td><a href="#" class="datalink" id="sr-aresdf"></a></td>
                                <td><a href="#" class="datalink" id="sr-aresmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=720516" target="_blank">ATAD5</a></td>
                                <td><a href="#" class="datalink" id="sr-atad5sdf"></a></td>
                                <td><a href="#" class="datalink" id="sr-atad5smiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=743228" target="_blank">HSE</a></td>
                                <td><a href="#" class="datalink" id="sr-hsesdf"></a></td>
                                <td><a href="#" class="datalink" id="sr-hsesmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=720637" target="_blank">MMP</a></td>
                                <td><a href="#" class="datalink" id="sr-mmpsdf"></a></td>
                                <td><a href="#" class="datalink" id="sr-mmpsmiles"></a></td>
                            </tr>
                            <tr><td><a href="https://pubchem.ncbi.nlm.nih.gov/assay/assay.cgi?aid=720552" target="_blank">p53</a></td>
                                <td><a href="#" class="datalink" id="sr-p53sdf"></a></td>
                                <td><a href="#" class="datalink" id="sr-p53smiles"></a></td>
                            </tr>
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                    <div class="panel-heading"><h3 class="panel-title">Final Evaluation <span class="glyphicon glyphicon-cloud-download bs-icon"> </span></h3></div>
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                        <p><br/>The final evaluation dataset is now
                available for download as either <a href="download?id=tox21_10k_challenge_scoresmiles&sec=">SMILES</a> or
                <a href="download?id=tox21_10k_challenge_scoresdf&sec=">SDF</a>.
                Results submitted for this dataset will be used to
                determine the final ranking of the
                competition. Note that you can submit multiple times
                but only the latest submission will be used for
                scoring. You can continue submitting to the
                leaderboard to test your model until October
                13<sup>th</sup>, 2014, after which time the
                leaderboard will be closed and submissions thereafter
                will be toward the final evaluation set.
                    </div>
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                    <div class="panel-heading"><h3 class="panel-title">Testing Dataset <span class="glyphicon glyphicon-cloud-download bs-icon"> </span></h3></div>
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                        <p><br/>The testing dataset is available for download 
                            <a href="download?id=tox21_10k_challenge_testsmiles&sec=">here</a>.
                            Please note this dataset is only used to evaluate performance 
                            for the leaderboard; a separate dataset will be used 
                            to determine the winner.
                        <p>Results for the testing dataset are now available for 
                            <a href="download?id=tox21_10k_challenge_testsdf&sec=">download</a>.
                    </div>
                </div>
            </div>
        

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                <div class="panel-heading"><h3 class="panel-title">Public Domain Code <span class="glyphicon glyphicon-cloud-download bs-icon"> </span></h3></div>
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                    <br><p> The following are links to code developed by our group that might be useful for the challenge.
                    Please feel free to <span id="contactus"></span> for any
                    questions about the code. 
                    <ul>
                       <li> <a href="https://github.com/ncats/lychi">LyChI</a> is a structure standardizer 
                       that can be used to remove salts and solvents.
                       <li> <a href="https://bitbucket.org/caodac/pcfp">PCFP</a> is our implementation of 
                       the <a href="ftp://ftp.ncbi.nlm.nih.gov/pubchem/specifications/pubchem_fingerprints.txt">PubChem fingerprint</a>.
                       <li>A number of molecular descriptors (e.g., topological indices, group contribution, 
                       solvent accessible surface area, etc.) are available as part of the 
                       <a href="https://bitbucket.org/caodac/reagents">library synthesizer</a> code base.
                       <li><a href="https://github.com/ncats/tox21baseline">Tox21Baseline</a>
                              is a simple implementation of the 
                              <a href="http://en.wikipedia.org/wiki/Naive_Bayes_classifier">naive Bayes</a> 
                              classifier&mdash;utilizing LyChI for 
                              structure standardization and PCFP for descriptor/feature extraction&mdash;to 
                              provide baseline models for the 12 datasets in the challenge.
                    </ul>
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